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Abstract Analogous of pixels to two-dimensional pictures, voxels—in the form of either small cubes or spheres—are the basic building blocks of three-dimensional objects. However, precise manipulation of viscoelastic bio-ink voxels in three-dimensional space represents a grand challenge in both soft matter science and biomanufacturing. Here, we present a voxelated bioprinting technology that enables the digital assembly of interpenetrating double-network hydrogel droplets made of polyacrylamide/alginate-based or hyaluronic acid/alginate-based polymers. The hydrogels are crosslinked via additive-free and biofriendly click reaction between a pair of stoichiometrically matched polymers carrying norbornene and tetrazine groups, respectively. We develop theoretical frameworks to describe the crosslinking kinetics and stiffness of the hydrogels, and construct a diagram-of-state to delineate their mechanical properties. Multi-channel print nozzles are developed to allow on-demand mixing of highly viscoelastic bio-inks without significantly impairing cell viability. Further, we showcase the distinctive capability of voxelated bioprinting by creating highly complex three-dimensional structures such as a hollow sphere composed of interconnected yet distinguishable hydrogel particles. Finally, we validate the cytocompatibility and in vivo stability of the printed double-network scaffolds through cell encapsulation and animal transplantation. 

Abstract Previous observational and modeling studies have suggested that moisture plays a dominant role in Madden–Julian oscillation (MJO) evolution. Using a realistic MJO simulation by incorporating the role of mesoscale stratiform heating in the Zhang–McFarlane deep convection scheme in the National Center for Atmospheric Research Community Atmosphere Model, version 5.3 (NCAR CAM5.3), this study investigates the factors responsible for the improved MJO simulation by examining moisture variations during different MJO phases. The results of column moist static energy (MSE) and moisture budgets show that during the suppressed phases of MJO, vertical advection acts to increase MSE anomalies for the development of deep convection while radiative heating and surface heat flux decrease MSE. The opposite holds true at the MJO mature phase. However, their roles largely cancel each other, leaving horizontal advection to play a major role in the low-level MSE increase during the suppressed phase of the MJO and MSE decrease after the MJO mature phase. A further analysis combining moisture and temperature budget equations is performed to demonstrate the effects of vertical advection and cloud processes within the column at each level. The vertical profiles of column-confined moisture tendency show that large-scale vertical advection induced by latent heat release and evaporation within shallow convective clouds is also important to the lower-tropospheric moistening during suppressed phases. This confirms the role of shallow convection in low-level moistening ahead of MJO deep convection. Radiative heating is vital across all MJO phases, and its warming effects keep the column humidity anomaly maintained in mature phases. None of these features are reproduced by the standard CAM5.3. 

Abstract Humid heat waves pose significant risks to human health and the ecosystem. Intuitively, rainfall often alleviates extreme humid heat. However, here we show that light rain often accompanies extreme humid heat, exacerbating its frequency and intensity, especially over arid and semi-arid regions compared to no rain and moderate-to-heavy rain cases. This is because light rain does not dramatically reduce solar radiation but increases near-surface humidity through enhanced surface evaporation. The water replenishment from light rain as well as a shallower planetary boundary layer is crucial for consecutive extremes where there are commonly sporadic drizzle days amidst several rain-free days. These extremes last longer than rain-free extremes. Current global climate models (GCMs) overestimate light rain. After reducing this bias in a GCM, underestimations of humid heat waves in energy-limited regions and overestimations in water-limited regions are largely alleviated. These findings underscore the underappreciated impact of light rain on extreme humid heat. 

The space hurricane is a newly discovered large-scale three-dimensional magnetic vortex structure that spans the polar ionosphere and magnetosphere. It has been suggested to open a fast energy transport channel for the solar wind to invade Earth’s magnetosphere under northward interplanetary magnetic field (IMF) conditions. It is, therefore, an important phenomenon to understand the solar wind–magnetosphere–ionosphere coupling process under northward IMF conditions. In this study, we report the three-dimensional ionospheric plasma properties of a space hurricane event in the Northern Hemisphere observed by multiple instruments. Based on the convection velocity observations from ground-based radars and polar satellites, we confirm that the major modulation to the polar cap convection called a space hurricane rotates clockwise at the altitude of the ionosphere. Ground-based incoherent scatter radar and polar satellite observations reveal four features associated with the space hurricane: 1) strong plasma flow shears and being embedded in a clockwise lobe convection cell; 2) a major addition to the total energy deposition in the ionosphere–thermosphere system by Joule heating; 3) downward ionospheric electron transport; and 4) multiple ion-temperature enhancements in the sunward velocity region, likely from the spiral arms of the space hurricane. These results present, first, the impact of space hurricane on the low-altitude ionosphere and provide additional insights on the magnetospheric impact on structuring in the polar ionosphere.